Immunomodulatory Effect of Irreversible Electroporation Alone and Its Cooperating With Immunotherapy in Pancreatic Cancer
Guo Tian, Jiajia Guan, Yanhua Chu, Qiyu Zhao, Tianan Jiang
Abstract
Emerging studies have showed irreversible electroporation (IRE) focused on pancreatic cancer (PC). However, the effects of IRE treatment on the immune response of PC remain unknown. Moreover, there are few studies on the therapeutic effect of IRE combining with immunotherapy on PC. Thus, we review recent advances in our understanding of IRE alone and its working with immunotherapy towards the immune response of PC, discussing potential opportunities for exploring future treatment strategies.
Topics & Concepts
Irreversible electroporationImmunotherapyElectroporationMedicineImmune systemPancreatic cancerCancer immunotherapyCancer researchCancerImmunologyInternal medicineBiologyGeneBiochemistryMicrobial Inactivation MethodsToxin Mechanisms and ImmunotoxinsTransgenic Plants and Applications