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Optimized integration of fluoxetine and 7, 8-dihydroxyflavone as an efficient therapy for reversing depressive-like behavior in mice during the perimenopausal period

Nashwa Amin, Shiyi Xie, Xiaoning Tan, Yili Chen, Qiannan Ren, Benson O. A. Botchway, Shaohua Hu, Yongchun Ma, Zhiying Hu, Marong Fang

2020Progress in Neuro-Psychopharmacology and Biological Psychiatry44 citationsDOI

Topics & Concepts

Protein kinase BPI3K/AKT/mTOR pathwayWestern blotTropomyosin receptor kinase BBrain-derived neurotrophic factorPharmacologyMAPK/ERK pathwayChemistryNeurotrophic factorsKinaseEndocrinologyInternal medicinePhosphorylationMedicineReceptorSignal transductionBiochemistryGeneTryptophan and brain disordersNeurogenesis and neuroplasticity mechanismsStress Responses and Cortisol
Optimized integration of fluoxetine and 7, 8-dihydroxyflavone as an efficient therapy for reversing depressive-like behavior in mice during the perimenopausal period | Litcius