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Ferroptosis inhibitor improves cardiac function more effectively than inhibitors of apoptosis and necroptosis through cardiac mitochondrial protection in rats with iron-overloaded cardiomyopathy

Sirinart Kumfu, Jirapas Sripetchwandee, Chanisa Thonusin, Natticha Sumneang, Chayodom Maneechote, Busarin Arunsak, Titikorn Chunchai, Thura Tun Oo, Aphisek Kongkaew, Siriporn C. Chattipakorn, Nipon Chattipakorn

2023Toxicology and Applied Pharmacology14 citationsDOI

Topics & Concepts

NecroptosisProgrammed cell deathDeferoxamineApoptosisCardiac function curveMitochondrionCardiomyopathyPharmacologyMedicineCancer researchCell biologyBiologyInternal medicineHeart failureBiochemistryIron Metabolism and DisordersTrace Elements in HealthHemoglobinopathies and Related Disorders
Ferroptosis inhibitor improves cardiac function more effectively than inhibitors of apoptosis and necroptosis through cardiac mitochondrial protection in rats with iron-overloaded cardiomyopathy | Litcius