The Omicron BA.2.2.1 subvariant drove the wave of SARS-CoV-2 outbreak in Shanghai during spring 2022
Yun Ling, Gang Lü, Feng Liu, Yun Tan, Xiaoguang Xu, Dong Wei, Jinkun Xu, Shuai Wang, Shuting Yu, Fangying Jiang, Xinxin Zhang, Shuo Chen, Shengyue Wang, Xiaohong Fan, Sai‐Juan Chen
Abstract
As the SARS-CoV-2 virus spreads around the globe, a number of variants of concern (VOCs) have successively dominated geographical incidences of the pandemic of coronavirus disease 2019 (COVID-19) These VOCs are characterized by particular constellations of genetic mutations that are often associated with the change of molecular features of viral proteins promoting viral infectivity and transmissibility, as well as clinical manifestations 3 . Therefore, tracing the origin and spreading patterns of emerging SARS-CoV-2 variants is critical for evaluating and guiding the measures to ameliorate the impact of the virus on public health.