Amino acid containing amphiphilic hydrogelators with antibacterial and antiparasitic activities
Biplab Mondal, Vivek Gupta, Biswanath Hansda, Arpita Bhoumik, Tanushree Mondal, Hemanta K. Majumder, Charlotte J. C. Edwards‐Gayle, Ian W. Hamley, Parasuraman Jaisankar, Arindam Banerjee
Abstract
and trigger apoptotic-like events inside the parasite. The mechanism of killing the parasite is shown and these gelators are non-cytotoxic to host macrophage cells indicating the potential use of these gels as therapeutic agents against multiple forms of leishmaniasis in the near future.
Topics & Concepts
AmphiphileAntiparasiticPeptideResidue (chemistry)ChemistryBacteriaLeishmania donovaniAntibacterial activityAmino acidAntiparasitic agentBiochemistryLeishmaniaStereochemistryBiologyOrganic chemistryParasite hostingPharmacologyGeneticsPolymerWorld Wide WebComputer scienceCopolymerMedicinePathologyResearch on Leishmaniasis StudiesPeptidase Inhibition and AnalysisNeuropeptides and Animal Physiology