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A nucleotide-switch mechanism mediates opposing catalytic activities of Rel enzymes

Hedvig Tamman, Katleen Van Nerom, Hiraku Takada, Niels Vandenberk, Daniel Scholl, Yury S. Polikanov, Johan Hofkens, Ariel Talavera, Vasili Hauryliuk, Jelle Hendrix, Abel García-Pino

2020Nature Chemical Biology49 citationsDOIOpen Access PDF

Topics & Concepts

Mechanism (biology)EnzymeNucleotideCell biologyChemistryBiochemistryBiologyGeneticsGeneEpistemologyPhilosophyEnzyme Structure and FunctionBiochemical and Molecular ResearchAmino Acid Enzymes and Metabolism
A nucleotide-switch mechanism mediates opposing catalytic activities of Rel enzymes | Litcius