Litcius/Paper detail

Docosahexaenoic acid (DHA), an omega-3 fatty acid, inhibits tumor growth and metastatic potential of ovarian cancer.

Lindsay West, Yajie Yin, Stuart R. Pierce, Ziwei Fang, Yali Fan, Wenchuan Sun, Katherine L. Tucker, Allison Staley, Chunxiao Zhou, Victoria Bae‐Jump

2020PubMed40 citationsOpen Access PDF

Abstract

mouse model of ovarian cancer including downregulation of Ki67 and VEGF expression. The data provide a preclinical rationale for applying DHA for dietary intervention and therapeutic adjunct in patients with ovarian cancer.

Topics & Concepts

Docosahexaenoic acidOvarian cancerCancer researchApoptosisPolyunsaturated fatty acidDownregulation and upregulationFish oilReactive oxygen speciesCancerCell growthEicosapentaenoic acidBiologyFatty acidChemistryMedicineInternal medicineBiochemistryFish <Actinopterygii>GeneFisheryCancer, Lipids, and MetabolismFatty Acid Research and HealthEicosanoids and Hypertension Pharmacology