Tumor-associated macrophages induce inflammation and drug resistance in a mechanically tunable engineered model of osteosarcoma
Letitia K. Chim, Isabelle L. Williams, Caleb J. Bashor, Antonios G. Mikos
Topics & Concepts
OsteosarcomaTumor microenvironmentCancer researchTumor necrosis factor alphaInflammationCD44STAT3Immune systemSTAT proteinCellBiologyCell biologyMaterials scienceImmunologySignal transductionGeneticsHippo pathway signaling and YAP/TAZCellular Mechanics and InteractionsCancer Cells and Metastasis