Antagonism of the brain P2X7 ion channel attenuates repeated social defeat induced microglia reactivity, monocyte recruitment and anxiety-like behavior in male mice
Rebecca G. Biltz, Samuel P. Swanson, Natalie Draime, Amara C. Davis, Wenyuan Yin, Ethan Goodman, Natalie R. Gallagher, Anindya Bhattacharya, John F. Sheridan, Jonathan P. Godbout
Topics & Concepts
MicrogliaPurinergic receptorMonocyteNeuroinflammationAntagonismSocial defeatPharmacologyAntagonistChemokineReceptorEndocrinologyMedicineInternal medicineInflammationTryptophan and brain disordersNeuroinflammation and Neurodegeneration MechanismsAdenosine and Purinergic Signaling