IRE1 signaling pathway mediates protective autophagic response against manganese-induced neuronal apoptosis in vivo and in vitro
Chang Liu, Dongying Yan, Can Wang, Zhuo Ma, Yu Deng, Wei Liu, Bin Xu
Topics & Concepts
AutophagyUnfolded protein responseCell biologyEndoplasmic reticulumASK1ULK1Signal transductionBAG3ATF4NeurotoxicityChemistryTRAF2KinaseProtein kinase ABiologyApoptosisAMPKMitogen-activated protein kinase kinaseBiochemistryOrganic chemistryTumor necrosis factor receptorToxicityAutophagy in Disease and TherapyEndoplasmic Reticulum Stress and DiseaseCassava research and cyanide