Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments
Xin Sheng, Yuting Guan, Ziyuan Ma, Junnan Wu, Hongbo Liu, Chengxiang Qiu, Steven Vitale, Zhen Miao, Matthew J. Seasock, Matthew Palmer, Myung K. Shin, Kevin L. Duffin, Steven S. Pullen, Todd L. Edwards, Jacklyn N. Hellwege, Adriana M. Hung, Mingyao Li, Benjamin F. Voight, Thomas M. Coffman, Christopher D. Brown, Katalin Suszták
Topics & Concepts
BiologyGenetic architectureDiseaseComputational biologyEvolutionary biologyHuman diseaseGeneticsKidney diseasePhenotypeGeneInternal medicineEndocrinologyMedicineGenetic Associations and EpidemiologySingle-cell and spatial transcriptomicsDiabetes and associated disorders