Litcius/Paper detail

Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments

Xin Sheng, Yuting Guan, Ziyuan Ma, Junnan Wu, Hongbo Liu, Chengxiang Qiu, Steven Vitale, Zhen Miao, Matthew J. Seasock, Matthew Palmer, Myung K. Shin, Kevin L. Duffin, Steven S. Pullen, Todd L. Edwards, Jacklyn N. Hellwege, Adriana M. Hung, Mingyao Li, Benjamin F. Voight, Thomas M. Coffman, Christopher D. Brown, Katalin Suszták

2021Nature Genetics164 citationsDOIOpen Access PDF

Topics & Concepts

BiologyGenetic architectureDiseaseComputational biologyEvolutionary biologyHuman diseaseGeneticsKidney diseasePhenotypeGeneInternal medicineEndocrinologyMedicineGenetic Associations and EpidemiologySingle-cell and spatial transcriptomicsDiabetes and associated disorders