A chemically inducible IL-2 receptor signaling complex allows for effective in vitro and in vivo selection of engineered CD4+ T cells
Peter J. Cook, Su Jung Yang, Gene Uenishi, Annaiz Grimm, Samuel E. West, Lijie Wang, Chester Jacobs, Andrea Repele, Travis Drow, Ahmad Boukhris, Noelle Dahl, Karen Sommer, Andrew M. Scharenberg, David J. Rawlings
Topics & Concepts
In vivoCell biologyBiologyT-cell receptorFOXP3CD19Chimeric antigen receptorIn vitroT cellCancer researchImmunologyAntigenImmune systemGeneticsCAR-T cell therapy researchImmune Cell Function and InteractionT-cell and B-cell Immunology