Novel anilinopyrimidine derivatives as potential EGFRT790M/C797S Inhibitors: Design, Synthesis, biological activity study
Yanliang Guo, Biao Gao, Peng Gao, Lei Fang, Shaohua Gou
Topics & Concepts
ChemistryT790MKinasePharmacologyIn vivoCell cultureCancer researchBiochemistryReceptorEpidermal growth factor receptorMedicineBiologyBiotechnologyGefitinibGeneticsCancer therapeutics and mechanismsLung Cancer Treatments and MutationsQuinazolinone synthesis and applications