Discovery of novel steroidal-chalcone hybrids with potent and selective activity against triple-negative breast cancer
Qiangqiang Hou, Xin Lin, Xiang Lu, Chengfeng Bai, Hanlin Wei, Guoshun Luo, Hua Xiang
Topics & Concepts
ChalconeTriple-negative breast cancerChemistryApoptosisCytotoxic T cellCancer cellCytotoxicityCell cycle checkpointCell cycleMTT assayCancer researchCell growthCancerIn vitroBreast cancerBiochemistryStereochemistryBiologyGeneticsSynthesis and biological activityBioactive Compounds and Antitumor AgentsGenomics, phytochemicals, and oxidative stress