Litcius/Paper detail

Structures and Biological Activities of Alkaloids Produced by Mushrooms, a Fungal Subgroup

Jesús G. Zorrilla, Antonio Evidente

2022Biomolecules45 citationsDOIOpen Access PDF

Abstract

-containing natural products, whose research has revealed bioactive compounds of pharmacological interest. Studies on these compounds have focused more attention on those produced by plants, although other types of organisms have also been proven to synthesize bioactive alkaloids, such as animals, marine organisms, bacteria, and fungi. This review covers the findings of the last 20 years (2002-2022) related to the isolation, structures, and biological activities of the alkaloids produced by mushrooms, a fungal subgroup, and their potential to develop drugs and agrochemicals. In some cases, the synthesis of the reviewed compounds and structure-activity relationship studies have been described.

Topics & Concepts

BiologyIsolation (microbiology)AntifungalBiological activityChemistryMicrobiologyBiochemistryIn vitroChemical synthesis and alkaloidsFungal Biology and ApplicationsCholinesterase and Neurodegenerative Diseases