Preparation and characterization of electrospun shape memory polyurethane/graphene quantum dot nanocomposite scaffolds for tissue engineering
Sanaz Sarabiyan Nejad, Donya Razzaghi, Mostafa Rezaei, Massuomeh Bagheri, Amin Babaie, Farhang Abbasi
Abstract
Shape memory polyurethane (SMPU)/graphene quantum dot nanoparticles (GQDs) nanofibers were prepared by electrospinning technique. Results show that the localization of GQD nanoparticles into the nanocomposite electrospun nanofibers has increased the nanofiber average diameter. An increment has been observed in the mechanical strength of nanocomposite nanofiber mats. More uniform and straight nanofibers have been obtained for PU-0.5% due to the relative electrical conductivity induced by the presence of GQD nanoparticles. Presence of crystallizable polycaprolactone (PCL) soft segment in PU structure induced shape memory potential in electrospun scaffolds. In vitro study showed PU-0.5% scaffold had good interaction with 3T3 fibroblast cells.