Redox Activity and Nano–Bio Interactions Determine the Skin Injury Potential of Co<sub>3</sub>O<sub>4</sub>-Based Metal Oxide Nanoparticles toward Zebrafish
Guotao Peng, Yuan He, Xiaoxiao Wang, Yan Cheng, Haiyuan Zhang, Kai Savolainen, Lutz Mädler, Suman Pokhrel, Sijie Lin
Abstract
genes. Although the exposure to the nanoparticles alone was not lethal, the skin injury did lower the tolerance level against other environmental contaminants. More importantly, after withdrawing from the nanoparticle exposure, larvae with skin injury could recover within 24 h in uncontaminated medium, indicating such injury was transient and recoverable.
Topics & Concepts
Oxidizing agentRedoxZebrafishNanoparticleOxideImmune systemMetalNanomaterialsBiophysicsMaterials scienceChemistryNanotechnologyBiologyBiochemistryInorganic chemistryImmunologyGeneOrganic chemistryMetallurgyZebrafish Biomedical Research ApplicationsNeuroinflammation and Neurodegeneration MechanismsNanoparticles: synthesis and applications