Synthesis and Biological Activity Study of Tanshinone Derivatives: A Literature and Patent Review
He Huang, Chuanjun Song, Junbiao Chang
Abstract
Tanshinones are a class of bioactive compounds present in the Chinese herbal medicine Danshen (Salvia miltiorrhiza Bunge), containing among others, abietane diterpene quinone scaffolds. Chemical synthesis and biological activity studies of natural and unnatural tanshinone derivatives have been reviewed in this article.
Topics & Concepts
Salvia miltiorrhizaAbietaneDiterpeneChemistryTraditional medicineBiological activityTraditional Chinese medicineStereochemistryMedicineBiochemistryIn vitroPathologyAlternative medicineTraditional Chinese Medicine AnalysisPhytochemistry and Biological ActivitiesNatural product bioactivities and synthesis