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Assessment of the Kochak-Benet Equation for Hepatic Clearance for the Parallel-Tube Model: Relevance of Classic Clearance Concepts in PK and PBPK

William J. Jusko, Xiao‐Nan Li

2021The AAPS Journal18 citationsDOIOpen Access PDF

Topics & Concepts

Physiologically based pharmacokinetic modellingPharmacokineticsClearanceRelevance (law)Metabolic clearance rateComputer scienceCalculus (dental)PharmacologyMedicineUrologyPolitical scienceLawDentistryDrug Transport and Resistance MechanismsPharmacogenetics and Drug MetabolismLiver Disease Diagnosis and Treatment
Assessment of the Kochak-Benet Equation for Hepatic Clearance for the Parallel-Tube Model: Relevance of Classic Clearance Concepts in PK and PBPK | Litcius