GPR146 regulates pulmonary vascular remodeling by promoting pulmonary artery smooth muscle cell proliferation through 5-lipoxygenase
Jie Huang, Yongpeng Xie, Bing Chen, Yu Xia, Yanjiao Jiang, Zengxian Sun, Yun Liu
Topics & Concepts
Hypoxia (environmental)Pulmonary hypertensionPulmonary arteryRight ventricular hypertrophyGene knockdownMedicineLungVascular smooth muscleMuscle hypertrophyVascular resistanceCardiologyInternal medicineApoptosisCancer researchPharmacologyBlood pressureBiologyChemistrySmooth muscleBiochemistryOrganic chemistryOxygenPulmonary Hypertension Research and TreatmentsEicosanoids and Hypertension PharmacologyNitric Oxide and Endothelin Effects