Design and synthesis of novel tacrine-dipicolylamine dimers that are multiple-target-directed ligands with potential to treat Alzheimer’s disease
Panpan Zhang, Ze Wang, Chenye Mou, Jiamei Zou, Yanfei Xie, Zhiwen Liu, C. Benjamin Naman, Yuechun Mao, Jiaxin Wei, Xinghan Huang, Jiahui Dong, Mengxiang Yang, Ning Wang, Haixiao Jin, Fufeng Liu, Dongdong Lin, Hao Liu, Zhou Fei, Shan He, Bin Zhang, Wei Cui
Topics & Concepts
TacrineChemistryAcetylcholinesteraseNeuroprotectionPharmacologyBiochemistryEnzymeMedicineCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsAlzheimer's disease research and treatments