Litcius/Paper detail

Safety, pharmacokinetics, and pharmacodynamics of LBP-EC01, a CRISPR-Cas3-enhanced bacteriophage cocktail, in uncomplicated urinary tract infections due to Escherichia coli (ELIMINATE): the randomised, open-label, first part of a two-part phase 2 trial

Paul Kim, Ana M. Sánchez, Taylor J.R. Penke, Hannah H. Tuson, J. Kime, Robert W. McKee, William L. Slone, Nicholas R. Conley, Lana J. McMillan, Cameron J. Prybol, Paul M. Garofolo

2024The Lancet Infectious Diseases85 citationsDOI

Topics & Concepts

DosingPharmacodynamicsAntibioticsEscherichia coliAntibiotic resistanceUrinary systemMedicineBacteriophagePharmacokineticsDrug resistancePharmacologyMicrobiologyIntensive care medicineBiologyInternal medicineGeneticsGeneCRISPR and Genetic EngineeringBacteriophages and microbial interactionsVibrio bacteria research studies