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In vivo affinity maturation of mouse B cells reprogrammed to express human antibodies

Yiming Yin, Yan Guo, Yuxuan Jiang, Brian D. Quinlan, Haiyong Peng, Gogce Crynen, Wenhui He, Lizhou Zhang, Tianling Ou, Charles C. Bailey, Michael Farzan

2024Nature Biomedical Engineering22 citationsDOIOpen Access PDF

Topics & Concepts

In vivoAntibodyCell biologyMolecular biologyChemistryBiologyImmunologyGeneticsMonoclonal and Polyclonal Antibodies ResearchCAR-T cell therapy researchT-cell and B-cell Immunology
In vivo affinity maturation of mouse B cells reprogrammed to express human antibodies | Litcius