Binding uric acid: a pure chemical solution for the treatment of hyperuricemia
Yunyun Li, Jing Li, Yan Li, Hongping Long, Wei Lin, Yikun Wang, Rong Tang, Xuewu Liu, Dejian Jiang, Shao Liu, Dongsheng Cao, Gui‐Shan Tan, Kang Xu, Wen‐Xuan Wang
Abstract
A binding partner designed for uric acid inhibits its precipitation and ionization, and shows an anti-hyperuricemia activity in vivo competitive with benzbromarone, as well as a favorable safety profile.
Topics & Concepts
BenzbromaroneHyperuricemiaUric acidChemistryIn vivoPrecipitationPharmacologyBiochemistryInternal medicineMedicineBiologyBiotechnologyMeteorologyPhysicsGout, Hyperuricemia, Uric AcidCase Reports on HematomasEosinophilic Disorders and Syndromes