The cytotoxic natural compound erianin binds to colchicine site of β-tubulin and overcomes taxane resistance
Wei Yan, Yongzhao Zhou, Xue Yuan, Peng Bai, Minghai Tang, Lijuan Chen, Haoche Wei, Jianhong Yang
Topics & Concepts
TubulinPaclitaxelColchicineMicrotubuleTaxaneCell cycleCell cycle checkpointBiologyChemistryApoptosisBiochemistryCell biologyCancerGeneticsBreast cancerBiological and pharmacological studies of plantsPlant Molecular Biology ResearchBioactive natural compounds