Magnetic Nanoparticle-Based Hyperthermia Mediates Drug Delivery and Impairs the Tumorigenic Capacity of Quiescent Colorectal Cancer Stem Cells
Soraia Fernandes, Tamara Fernández, Sabrina Metze, Preethi B. Balakrishnan, T. Binh, John S. Conteh, Claudia De Mei, Alice Turdo, Simone Di Franco, Giorgio Stassi, Matilde Todaro, Teresa Pellegrino
Abstract
when choosing the drug oxaliplatin rather than DOXO and applying MHT. These findings emphasize the potential of our nanoplatforms as an effective patient-personalized cancer treatment against qCR-CSCs.
Topics & Concepts
Cancer researchCancer stem cellHyperthermiaColorectal cancerMaterials scienceIn vitroMetastasisStem cellMagnetic hyperthermiaOxaliplatinCancer cellIn vivoCancerMagnetic nanoparticlesMedicineNanotechnologyChemistryCell biologyNanoparticleBiologyInternal medicineBiochemistryBiotechnologyCancer Cells and Metastasis3D Printing in Biomedical ResearchNanoparticle-Based Drug Delivery