Effect of osmotic pressure on pore formation in lipid bilayers by the antimicrobial peptide magainin 2
Md. Masum Billah, Samiron Kumar Saha, Md. Mamun Or Rashid, Farzana Hossain, Masahito Yamazaki
Abstract
Osmotic pressure ( Π ) induces membrane tension σ in giant unilamellar vesicles (GUVs), which elevates rate constant k p for antimicrobial peptide magainin 2-induced pore formation in GUVs. The process of its pore evolution in GUVs with σ was revealed.
Topics & Concepts
MagaininVesicleMembraneBiophysicsChemistryOsmotic pressureTension (geology)Lipid bilayerAntimicrobial peptidesPeptideBiochemistryMaterials scienceBiologyMetallurgyUltimate tensile strengthAntimicrobial Peptides and ActivitiesLipid Membrane Structure and BehaviorPolydiacetylene-based materials and applications