Enhancing the peroxidase-mimicking activity of hemin by covalent immobilization in polymer nanogels
Jieyu Guo, Yuting Liu, Junqi Zha, Hong-Hua Han, Yantao Chen, Zhongfan Jia
Abstract
A polymeric nanozyme that can closely mimic peroxidase is presented. The coordination between pendant hemins and primary amines together with the synergistic interactions between substrates and nanogels contribute to the enhanced catalytic activity.
Topics & Concepts
HeminPeroxidaseChemistryCovalent bondCombinatorial chemistryPolymerCatalysisPolymer chemistryOrganic chemistryEnzymeHemeAdvanced Nanomaterials in CatalysisElectrochemical sensors and biosensorsNanocluster Synthesis and Applications