New synthetic phenylquinazoline derivatives induce apoptosis by targeting the pro-survival members of the BCL-2 family
Samson Eugin Simon, Usman Ahmed, Syed Muhammad Saad, Ayaz Anwar, Khalid Mohammed Khan, Ee Wern Tan, Kuan Onn Tan
Topics & Concepts
Cancer cellChemistryCancer researchApoptosisSensitizationCancerCisplatinBreast cancerCytotoxicityCell growthSuppressorPharmacologyIn vitroBiologyBiochemistryImmunologyChemotherapyGeneticsGeneCell death mechanisms and regulationRNA Interference and Gene DeliveryProtein Degradation and Inhibitors