Ten golden rules for optimal antibiotic use in hospital settings: the WARNING call to action
Worldwide Antimicrobial Resistance National/International Network Group (WARNING) Collaborators, Massimo Sartelli, Philip S. Barie, Federico Coccolini, Mohamed Abbas, Lilian M. Abbo, Gulnora K. Abdukhalilova, Yishak Abraham, Salisu Abubakar, Fikri M. Abu‐Zidan, Yusuff Adebayo Adebisi, Harissou Adamou, Gulara Afandiyeva, Ervis Agastra, Wadha Alfouzan, Majdi N. Al‐Hasan, Sajjad Ali, Syed Muhammad Sinaan Ali, Fatima Allaw, Gbemisola Allwell-Brown, Afreenish Amir, Obed Kwabena Offe Amponsah, Abdelkarim Al Omari, Luca Ansaloni, Shamshul Ansari, Ana Belén Araúz, Goran Augustin, Bih Awazi, Mohammad Azfar, Mamadou Saliou Bailo Bah, Miklosh Bala, Anura S. K. Banagala, Suman Baral, Matteo Bassetti, Luis Bavestrello, Gregory J. Beilman, Kebebe Bekele, Moussa Benboubker, Bojana Beovič, Maria Daniela Bergamasco, Silvia Bertagnolio, Walter L. Biffl, Stijn Blot, Marja A. Boermeester, Robert A. Bonomo, Adrian Brink, Silvio Brusaferro, Jonathan Butemba, Miguel Caínzos, Adrián Camacho-Ortíz, Rafael Cantón, Antonio Cascio, Alessandro Cassini, Enrique Castro‐Sánchez, Marco Catarci, Rodolfo Catena, Leili Chamani‐Tabriz, Sujith J Chandy, Esmita Charani, William G. Cheadle, Diana Chebet, Ibrahim Chikowe, Francesca Chiara, Vincent Chi‐Chung Cheng, Anna Chioti, Maria Elena Cocuz, Raúl Coimbra, Francesco Cortese, Yunfeng Cui, Jacek Czepiel, Mira Dasic, Nataliya de Francisco Serpa, Stijn W. de Jonge, Samir Delibegović, E. Patchen Dellinger, Zaza Demetrashvili, Alessandra De Palma, Danushka De Silva, Belinda De Simone, Jan J. De Waele, Sameer Dhingra, José J. Diaz, Claudia Dima, Natalia Dirani, Cornelius C. Dodoo, Gereltuya Dorj, Therèse M. Duane, Christian Eckmann, Beverly Egyir, Mutasim M. Elmangory, Mushira Enani, Önder Ergönül, Juan Pablo Escalera-Antezana, Kevin Escandón-Vargas, Abdul-Wahab Omo-ope Ettu, Joseph Fadare, Massimo Fantoni, Mohammad Farahbakhsh, Mário Paulo Faro, Alberto R. Ferreres
Abstract
Antibiotics are recognized widely for their benefits when used appropriately. However, they are often used inappropriately despite the importance of responsible use within good clinical practice. Effective antibiotic treatment is an essential component of universal healthcare, and it is a global responsibility to ensure appropriate use. Currently, pharmaceutical companies have little incentive to develop new antibiotics due to scientific, regulatory, and financial barriers, further emphasizing the importance of appropriate antibiotic use. To address this issue, the Global Alliance for Infections in Surgery established an international multidisciplinary task force of 295 experts from 115 countries with different backgrounds. The task force developed a position statement called WARNING (Worldwide Antimicrobial Resistance National/International Network Group) aimed at raising awareness of antimicrobial resistance and improving antibiotic prescribing practices worldwide. The statement outlined is 10 axioms, or "golden rules," for the appropriate use of antibiotics that all healthcare workers should consistently adhere in clinical practice.