Pretreatment of exosomes derived from hUCMSCs with TNF-α ameliorates acute liver failure by inhibiting the activation of NLRP3 in macrophage
Shuqin Zhang, Linrui Jiang, Huazhong Hu, Hong Wang, Xiaoyan Wang, Jiaohua Jiang, Yanyan Ma, Jing Yang, Yu Hou, Denghui Xie, Qun Zhang
Topics & Concepts
Proinflammatory cytokineMicrovesiclesWestern blotInflammationMacrophageExosomeFlow cytometryChemistryTumor necrosis factor alphaMesenchymal stem cellIn vivoMolecular biologyCell biologymicroRNAImmunologyBiologyIn vitroBiochemistryBiotechnologyGeneExtracellular vesicles in diseaseInflammasome and immune disordersEndoplasmic Reticulum Stress and Disease