circROBO1 promotes prostate cancer growth and enzalutamide resistance via accelerating glycolysis
Zhigang Zhou, Jing Qin, Cailu Song, Tao Wu, Qiang Quan, Yan Zhang, Yani Zou, Lingrui Liu, Hailin Tang, Jianfu Zhao
Abstract
Our study identified the biological role of the circROBO1-miR-556-5p-PGK1 axis in the growth and enzalutamide resistance of prostate cancer, which is the potential therapeutic target of prostate cancer.
Topics & Concepts
Prostate cancerEnzalutamideGene knockdownCancer researchCancerDownregulation and upregulationmicroRNAProstateMedicineBiologyInternal medicineGeneAndrogen receptorBiochemistryCircular RNAs in diseasesMicroRNA in disease regulationCancer-related molecular mechanisms research