Electrogenerated Sm(II)-Catalyzed Carbon Dioxide Reduction for β-Hydrocarboxylation of Styrenes
Sakna Bazzi, Liangjian Hu, Emmanuelle Schulz, Mohamed Mellah
Abstract
The synthesis of carboxylic acids from low-value materials such as alkenes using CO 2 as a C 1 -building block remains a real challenge for synthetic chemists from both reactivity and selectivity perspectives. Electrochemical carboxylations have been examined but they remain limited, still suffering from a crucial lack of selectivity. Herein we report a catalytic protocol based on an electrogenerated Sm(II) catalyst as a powerful CO 2 reductant, able to perform exclusively anti -Markovnikov hydrocarboxylation of alkenes. This electrochemical approach overcomes several current limitations and allows direct β-hydrocarboxylation of styrene derivatives, in a regioselective manner.
Topics & Concepts
ChemistryRegioselectivityCatalysisSelectivityElectrochemistryMarkovnikov's ruleStyreneCombinatorial chemistryReactivity (psychology)Organic chemistryCopolymerElectrodePolymerPathologyMedicineAlternative medicinePhysical chemistryCarbon dioxide utilization in catalysisCO2 Reduction Techniques and CatalystsIonic liquids properties and applications