Phase 1 study of 2 high dose intensity schedules of the pan-Notch inhibitor crenigacestat (LY3039478) in combination with prednisone in patients with advanced or metastatic cancer
Analía Azaro, Capucine Baldini, Jordi Rodón, Jean‐Charles Soria, Eunice Yuen, Andrew Lithio, Gerard J. Oakley, Karim A. Benhadji, Christophe Massard
Topics & Concepts
MedicinePrednisonePharmacokineticsGastroenterologyPharmacodynamicsInternal medicineRashCancerAdverse effectPharmacologyInfectious Diseases and MycologyDevelopmental Biology and Gene RegulationPI3K/AKT/mTOR signaling in cancer