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Photocatalytic synthesis of 2-oxabicyclo[2.1.1]hexanes: cobalt-enhanced efficiency

Siyuan Tang, Zhan-Jie Wang, Jianyong Wu, Zhi-Xi Xing, Ze-Yi Du, Huan‐Ming Huang

2025Chemical Science17 citationsDOIOpen Access PDF

Abstract

We developed a photocatalytic [2π + 2σ] cycloaddition to access 2-oxabicyclo[2.1.1]hexanes promoted by cobalt for the first time. In vitro assessments including physicochemical and pharmacological evaluations are performed.

Topics & Concepts

CobaltPhotocatalysisChemistryOrganic chemistryCatalysisRadical Photochemical ReactionsOxidative Organic Chemistry ReactionsCatalytic C–H Functionalization Methods