New organoselenides (NSAIDs-Se derivatives) as potential anticancer agents: Synthesis, biological evaluation and in silico calculations
Xianran He, Yousong Nie, Min Zhong, Shaolei Li, Xiaolong Li, Yi Guo, Zhenming Liu, Yangguang Gao, Fei Ding, Dan Wen, Yongmin Zhang
Topics & Concepts
ChemistryApoptosisCancer cellCell cultureThioredoxin reductaseDocking (animal)In silicoCell growthPharmacologyCancer researchBiochemistryCancerThioredoxinEnzymeNursingGeneMedicineInternal medicineGeneticsBiologyOrganoselenium and organotellurium chemistryInflammatory mediators and NSAID effectsEstrogen and related hormone effects