Toxoplasma gondii Dissemination in the Brain Is Facilitated by Infiltrating Peripheral Immune Cells
Christine A. Schneider, Dario X. Figueroa Velez, Stephanie B. Orchanian, Lindsey A. Shallberg, Dritan Agalliu, Christopher A. Hunter, Sunil Gandhi, Melissa B. Lodoen
Abstract
T. gondii is a foodborne parasite that infects the brain and can cause fatal encephalitis in immunocompromised individuals. However, there is a limited understanding of how the parasites disseminate through the brain and evade immune clearance.
Topics & Concepts
Toxoplasma gondiiImmune systemToxoplasmosisBiologyEncephalitisImmunologyVirologyMedicineAntibodyVirusToxoplasma gondii Research StudiesCytomegalovirus and herpesvirus researchHerpesvirus Infections and Treatments