Design, synthesis, molecular docking, in silico ADMET profile and anticancer evaluations of sulfonamide endowed with hydrazone-coupled derivatives as VEGFR-2 inhibitors
Asmaa M Sayed, Fatma A. Taher, Mohammad Abdel-Samad, Mohamed S.A. El-Gaby, Khaled El‐Adl, Nashwa M. Saleh
Topics & Concepts
ChemistryHydrazoneStereochemistryHydrazine (antidepressant)CytotoxicitySulfonamideDocking (animal)Combinatorial chemistryMedicinal chemistryIn vitroBiochemistryMedicineNursingEnzyme function and inhibitionSynthesis and Reactions of Organic CompoundsSynthesis and Catalytic Reactions