An injectable supramolecular hydrogel as a self-drug-delivery system for local chemoimmunotherapy against melanoma
Sourabh Bera, Hemanta Kumar Datta, Parthasarathi Dastidar
Abstract
), triggering apoptosis. This unique all-in-one self-drug-delivery approach, wherein the hydrogel implant is made from the drug molecules itself providing both chemotherapy and immunotherapy in combating deadly melanoma, highlights the supramolecular chemistry-based bottom-up approach in cancer therapy.
Topics & Concepts
ChemoimmunotherapyMelanomaInternalizationIn vivoDrug deliveryDrugCancer researchSkin cancerImmunotherapyMedicineCancer immunotherapyCancerCD8Cancer cellImmune systemChemotherapyIn vitroPharmacologyChemistryImmunologySurgeryBiologyInternal medicineBiochemistryBiotechnologyReceptorOrganic chemistryNanoplatforms for cancer theranosticsImmune cells in cancerSupramolecular Self-Assembly in Materials