Trichromatic-emission and dual-ratio semiconducting polymer dots as fluorescent probe for simultaneous quantification of Cu<sup>2+</sup>and pH<i>in vitro</i>and<i>in vivo</i>
Qiang Zhang, Junyong Sun, Rongchao Zhang, Xueli Chen, Ningning Chen, Feng Gao
Abstract
Polymer dots emitting in the red, green and blue color regions, have been successfully applied as lysosome-targeting nanoprobes for the simultaneous detection and multicolor imaging of pH and Cu<sup>2+</sup>in HeLa cells and zebrafish.
Topics & Concepts
FluorescencePolymerHeLaIn vivoIn vitroChemistryLysosomeNanotechnologyBiophysicsMaterials scienceOpticsBiochemistryOrganic chemistryBiologyBiotechnologyPhysicsEnzymeAdvanced biosensing and bioanalysis techniquesAdvanced Nanomaterials in CatalysisCarbon and Quantum Dots Applications