Electrochemical Nanobiosensors for Detection of Breast Cancer Biomarkers
Veronika Gajdošová, Lenka Lorencová, Peter Kasák, Jan Tkáč
Abstract
This comprehensive review paper describes recent advances made in the field of electrochemical nanobiosensors for the detection of breast cancer (BC) biomarkers such as specific genes, microRNA, proteins, circulating tumor cells, BC cell lines, and exosomes or exosome-derived biomarkers. Besides the description of key functional characteristics of electrochemical nanobiosensors, the reader can find basic statistic information about BC incidence and mortality, breast pathology, and current clinically used BC biomarkers. The final part of the review is focused on challenges that need to be addressed in order to apply electrochemical nanobiosensors in a clinical practice.
Topics & Concepts
MicrovesiclesBreast cancerExosomeMedicineComputational biologymicroRNACancerInternal medicineChemistryBiologyGeneBiochemistryAdvanced biosensing and bioanalysis techniquesAdvanced Biosensing Techniques and ApplicationsAnodic Oxide Films and Nanostructures