Potential effectiveness and adverse implications of repurposing doxycycline in COVID-19 treatment
Lekshmi Narendrakumar, Iype Joseph, Sabu Thomas
Abstract
: 'Fighting disease with already existing antibiotics' and 'antimicrobial resistance progression' are like two arms of a balance that has to be carefully equilibrated. Any imbalance by the inappropriate or indiscriminate use of the repurposed drugs would cause a disastrous increase in antimicrobial resistance (AMR). Hence, cautious parallel assessment of potential long-term consequences of AMR is of great importance to mankind as its impacts would prevail even after the current pandemic.
Topics & Concepts
RepurposingDoxycyclineCoronavirus disease 2019 (COVID-19)Adverse effectMedicineIntensive care medicineAntimicrobial2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Antiparasitic agentAntibioticsHydroxychloroquineDrug repositioningAntiparasiticPharmacologyVirologyDrugBiologyInternal medicineMicrobiologyPathologyEcologyDiseaseInfectious disease (medical specialty)OutbreakCOVID-19 Clinical Research StudiesVitamin C and Antioxidants ResearchLong-Term Effects of COVID-19