Stereoselective synthesis of <i>C</i>-glycosides from glycals and organotrifluoroborate salts
Karwan Abdulmajed Othman, Yimin Xiang, Yue Wang, Nianyu Huang, Nengzhong Wang, Linxuan Li, Hui Yao
Abstract
Utilizing the stability and reactivity of aryltrifluoroborates, we developed a Pd-catalyzed stereoselective C -glycosylation with high yields and exclusive anomeric selectivity under mild conditions.
Topics & Concepts
StereoselectivityChemistryGlycosylationAmine gas treatingAmideGlycosideArylOrganic chemistryCombinatorial chemistryCatalysisBiochemistryAlkylCarbohydrate Chemistry and SynthesisGlycosylation and Glycoproteins ResearchChemical Synthesis and Analysis