Synergistic antitumor effect of 5-fluorouracil and withaferin-A induces endoplasmic reticulum stress-mediated autophagy and apoptosis in colorectal cancer cells.
Abdullah M. Alnuqaydan, Bilal Rah, Abdulmajeed G. Almutary, Shailender S. Chauhan
Abstract
M phase in CRC cells.
Topics & Concepts
Unfolded protein responseAutophagyApoptosisWithaferin AEndoplasmic reticulumCancer researchAnnexinPopulationChemistryProgrammed cell deathCancer cellBiologyCancerMedicineCell biologyInternal medicineBiochemistryPathologyAlternative medicineWithania somniferaEnvironmental healthAutophagy in Disease and TherapyPARP inhibition in cancer therapyPhytochemicals and Medicinal Plants