Extracellular vesicles from methicillin resistant <i>Staphylococcus aureus</i> stimulate proinflammatory cytokine production and trigger IgE-mediated hypersensitivity
Krisana Asano, Shouhei Hirose, Kouji Narita, Phawinee Subsomwong, Noriaki Kawai, Rojana Sukchawalit, Akio Nakane
Abstract
stimulation of the spleen cells with SaEVs. These results suggested that MRSA-derived EVs act as an immunostimulant that induces inflammatory response and IgE-mediated hypersensitivity after MRSA infection.
Topics & Concepts
Proinflammatory cytokineStaphylococcus aureusImmune systemMicrobiologyImmunologyBiologyCytokineImmunoglobulin ESpleenChemokineStaphylococcal infectionsInflammationAntibodyBacteriaGeneticsExtracellular vesicles in diseaseBacterial Infections and VaccinesInflammasome and immune disorders