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Establishment of tumor inflammasome clusters with distinct immunogenomic landscape aids immunotherapy

Qingyu Liang, Jianqi Wu, Xin Zhao, Shuai Shen, Chen Zhu, Tianqi Liu, Xiao Cui, Ling Chen, Chunmi Wei, Peng Cheng, Wen Cheng, Anhua Wu

2021Theranostics21 citationsDOIOpen Access PDF

Abstract

Our study conducted a systematical investigation on inflammasome signaling in various tumor types. These findings highlight the importance of inflammasome evaluation in tumor classification and provide a foundation for improving relevant therapeutic regimens.

Topics & Concepts

InflammasomeCarcinogenesisCancer researchSignal transductionCancerMedicineBiologyImmunologyInflammationGeneticsInternal medicineInflammasome and immune disordersFerroptosis and cancer prognosisinterferon and immune responses
Establishment of tumor inflammasome clusters with distinct immunogenomic landscape aids immunotherapy | Litcius