From molecules to medicine: thiol selective bioconjugation in synthesis of diagnostic and therapeutic radiopharmaceuticals
Iqra Bibi, Sajid Mushtaq, Kyo Chul Lee, Ji Ae Park, Jung Young Kim
Abstract
stability profiles, reaction kinetics, stability of resulting adducts, and overall impact on the targeting ability of radiolabeled biomolecules. The insights presented here aim to facilitate the development of highly efficient radiopharmaceuticals, initially in preclinical settings and ultimately in clinical applications.
Topics & Concepts
BioconjugationThiolChemistryPharmacologyCombinatorial chemistryNanotechnologyMedicineBiochemistryMaterials scienceChemical Synthesis and AnalysisMonoclonal and Polyclonal Antibodies ResearchRadiopharmaceutical Chemistry and Applications