The cytoskeleton actin binding protein filamin A impairs both IGF2 mitogenic effects and the efficacy of IGF1R inhibitors in adrenocortical cancer cells
Rosa Catalano, Elena Giardino, Donatella Treppiedi, Federica Mangili, Valentina Morelli, Francesca Marta Elli, A Șerban, Michaela Luconi, Massimo Mannelli, A. Spada, Maura Arosio, Giovanna Mantovani, Erika Peverelli
Topics & Concepts
FLNAFilaminInsulin-like growth factor 1 receptorAutocrine signallingMAPK/ERK pathwayCancer researchGrowth factorCell biologyBiologyChemistrySignal transductionReceptorCytoskeletonCellGeneticsAdrenal and Paraganglionic TumorsCancer, Hypoxia, and MetabolismPituitary Gland Disorders and Treatments