Molecular and Cellular Responses to the TYK2/JAK1 Inhibitor PF-06700841 Reveal Reduction of Skin Inflammation in Plaque Psoriasis
Karen Page, Mayte Suárez‐Fariñas, Maria Suprun, Weidong Zhang, Sandra Garcet, Judilyn Fuentes‐Duculan, Xuan Li, Matthew Scaramozza, Elizabeth Kieras, Christopher Banfield, James D. Clark, Andrew Fensome, James G. Krueger, Elena Peeva
Topics & Concepts
PsoriasisJanus kinaseTyrosine kinase 2Proinflammatory cytokineMedicineInflammationSignal transductionCancer researchImmunologyBiologyPathologyCytokineInternal medicineReceptorCell biologyGrowth factorPlatelet-derived growth factor receptorPsoriasis: Treatment and PathogenesisCytokine Signaling Pathways and InteractionsDermatology and Skin Diseases