G-quadruplex stabilizer Tetra-Pt(bpy) disrupts telomere maintenance and impairs FAK-mediated migration of telomerase-positive cells
Zhe Shen, Ruiling Zheng, Huamao Yang, Sunhui Xing, Xiangxiang Jin, Hao Yan, Jufan Zhu, Yanan Mei, Feng Lin, Xiaohui Zheng
Topics & Concepts
TelomeraseTelomereChemistryTelomerase reverse transcriptaseCell biologyMolecular biologyCancer cellFocal adhesionCell growthBiologyCancer researchDNAGeneSignal transductionCancerBiochemistryGeneticsAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry